NIA & NIH Aging Research Resources

Nationally representative longitudinal study of U.S. adults over age 50, covering health, cognition, employment, retirement, family, finances, biomarkers, and genetics.

Research Planner, harmonized variables, cross-national HRS-family datasets, questionnaires, publications, and specialized HCAP, Exposome, and End-of-Life portals.

Comparable cognitive and dementia assessment data linked to HRS-family studies across countries.

NIH precision-medicine cohort of more than one million U.S. participants across the lifespan, with electronic health records, surveys, physical measurements, wearables, and whole-genome sequencing analyzed in the cloud-based Researcher Workbench. Registered and Controlled Tier access requires an institutional Data Use and Registration Agreement.

Supports approved linkages between eligible NIA-funded research studies and Medicare or Medicaid claims for health-services and outcomes research.

Harmonized environmental-exposure measures and tools connected to population studies of aging.

Controlled platform for datasets, biospecimens, MRI and X-ray images from NIA-supported studies such as CALERIE, SWAN, LIFE, SOF, MOST, ASPREE, and STARRRS.

Long-running NIA study with repeated physiological, functional, imaging, biomarker, and clinical measurements across adulthood.

Healthy Aging in Neighborhoods of Diversity across the Life Span: longitudinal data emphasizing health disparities, socioeconomic conditions, biology, and environment.

Discovery and data-sharing environment for NIA-supported AD/ADRD consortia, including molecular, omics, imaging, model, and therapeutic-target resources.

NIA repository for Alzheimer’s disease and related dementias genetics, genomics, sequencing, and harmonized phenotype data, with open and qualified-access collections.

Searchable summaries of AD preclinical efficacy studies, with information about models, interventions, outcomes, rigor, and reproducibility.

Develops and characterizes next-generation animal models of late-onset Alzheimer’s disease and shares model information and associated data.

Target-validation evidence, assays, reagents, structural biology, medicinal chemistry, and drug-discovery tools for Alzheimer’s disease.

Single-cell and spatial resources describing cellular and molecular changes across Alzheimer’s disease progression.

Neuroimaging, behavioral, and cognitive data designed to characterize structural and functional brain changes across healthy aging.

Standardized clinical, neuropathology, imaging, biomarker, and genetic data contributed by the national network of NIA Alzheimer’s Disease Research Centers.

Research and analytical resources for understanding individual differences in cognitive aging, reserve, resilience, and vulnerability.

Collaborative network and measurement resources focused on cognitive reserve and resilience in aging and AD/ADRD.

Subsidized aged mice and rats for aging research, with multiple strains, age ranges, and sex options.

Archived tissues from aged rodents for approved aging-research projects.

Human and animal cell lines related to aging, longevity, progeroid syndromes, age-associated disease, and comparative biology, maintained by Coriell.

Longitudinal information on nonhuman primate aging, including health, physiology, body composition, and survival.

Tissues and related materials from aged nonhuman primates for approved comparative and translational studies.

Multi-site testing of compounds for effects on lifespan and healthspan in genetically heterogeneous mice. Investigators may nominate interventions.

Public survival, phenotype, intervention, and protocol data produced by the NIA Interventions Testing Program.

Tissues from selected ITP intervention studies for ancillary mechanistic analyses of lifespan and healthspan.

Multi-site intervention testing across genetically diverse Caenorhabditis species, with public data, methods, and opportunities to propose compounds.

Longitudinal phenotypes, neuroimaging, tissues, and biological samples from a Long Evans rat model of reserve, resilience, and neurocognitive aging.

Shared aging-biology cores, specialized technologies, consultation, training, pilot awards, and collaborative opportunities.

Mentoring, methods support, pilot funding, and professional development for investigators studying aging and health disparities.

Support for translating behavioral and social science discoveries into practical interventions that improve the lives of older adults.

Pilot funding, engineering and commercialization support, testbeds, datasets, and stakeholder engagement for aging-related technologies.

NIH intramural hub for AD/ADRD genetics, biomarkers, disease modeling, target validation, open science, and precision therapeutics.

Conceptual framework, guidance, examples, and training for developing, refining, and testing behavioral interventions.

Search funded NIH projects, investigators, institutions, abstracts, publications, patents, and award spending.

Paste a project abstract to find scientifically similar funded projects and potentially relevant NIH institutes and study sections.

Successful sample applications and examples of biosketches, data-management plans, and other application materials.

Offers eligible early-career investigators an opportunity to gain practical NIH peer-review experience.

Fellowships, career-development awards, institutional training programs, and resources for new and early-stage aging researchers.

SBIR/STTR funding information, commercialization assistance, entrepreneurial training, webinars, and accelerator opportunities.